Held under the slogan «Alps & People», the fourth edition of AlpWeek was dedicated to the many aspects of the connections between the Alps and the people who live, work and spend their spare time there. The population of the Alps is facing major challenges and is at the same time the main player able to tackle these. One of the aims of AlpWeek was an exchange to allow new, Alpine-specific solutions to be found that will enhance the social, cultural and natural heritage of this region. The three topics of demography, culture and quality of life were addressed by numerous plenary presentations, sessions, field trips and a project forum. The fourth edition of AlpWeek was held in October 2016 in Grassau in Germany. The main objective is to enable meetings, dialogue and co-operation between a large number of participants who are committed to the sustainable development of the Alps. Also involved were politicians from local to national level, public authorities, scientists and students, NGOs and interested citizens. AlpWeek is also intended to facilitate discussion of the current and future challenges that concern and affect these players. This report summarises the most important elements regarding the three topics of demography, culture and quality of life that were covered in the lectures and sessions. In conclusion there is a review of the results of AlpWeek 2016 and proposals for the future direction of the event.